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Evaluation of efficacy of QR678® and QR678® Neo hair growth factor formulation in the treatment of persistent chemotherapy-induced alopecia caused due to cytotoxic chemotherapy-
A prospective pilot study

AbstractBackground:
Cancers are one of the main reasons of morbidity and mortality globally. Chemotherapy-induced alopecia (CIA) is one of the most alarming, terrifying, and
traumatic adverse effects. A range of therapeutic measures has been suggested to alleviate CIA, but at present, there is no accepted pharmacological therapy that can assure prevention or management.
Aim: The aim of the present study was to evaluate the efficacy of QR 678 Neo® therapy in the treatment of persistent chemotherapy-induced alopecia in women and men treated with cytotoxic chemotherapy for breast and lung cancers, respectively.
Methods: A total of 8 male patients with history of lung cancer and 12 female patients with history of breast cancer in the age range of 25-60 years, with WHO classification of grade I and II persistent alopecia who had undergone chemotherapy treatment, were selected for the study. At each visit, 1.5 mL solution of QR 678® was injected into the scalp skin of patients. A total of 8 sessions were performed at an interval of 3 weeks each. All the patients were evaluated with standard global photography, video microscopic assessment, and patient self-assessment questionnaire at baseline, 6 months, and 1 year.
Results: Marked improvement was seen in the global assessment score at 6 months (mean-8) which was maintained even after 1 year. Mean score increase in hair count at 6 months was 12.71 which further increased at 1 year. High satisfaction score was given by patients for slowing of hair loss (mean = 4.2) and also for overall hair growth. For appearance and growth of hair, the mean value was 3.4 and 3.8, respectively.
Conclusion: The formulation of QR 678® and QR 678® Neo showed to be significantly safe and efficient for chemotherapy-induced alopecia in both men and women. Improvement in hair growth was maintained even at 1 year of follow-up. No patient had any severe adverse effects, and injections were also easily bearable by most of them.
KEYWORDS
chemotherapy-induced alopecia, hair loss, QR678, QR678 Neo; hair growth

QR678 NEO: NATURAL INGREDIENTS
BACKED BY SCIENCE

The QR678® Neo therapy is a proprietary, first-in-class therapy, backed by science that arrests hair fall & increases the thickness, number, and density of existing hair follicles leading to greater coverage in hair loss. The biomimetic polypeptides used in the formulation mimic the action of specific human hair growth related growth factors that are naturally present in our scalp, making it natural growth factor-based treatment. The polypeptides penetrate deep into the scalp and provide nourishment to the scalp, which results in hair growth. Unlike other treatments that contains minoxidil & finasteride, QR678® Neo therapy is completely devoid of side effects.

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QR678® Neo ADVANTAGES

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Quick & Effective (Single
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Non Surgical

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13+ Published Researched Clinical Trials Demonstrating Efficacy

LIFE CHANGING RESULTS

PRE TREATMENT

POST 6 SESSIONS

PRE TREATMENT

POST 6 SESSIONS

49 year old female was suffering from post chemotherapy induced hair loss. She achieved impressive results with QR678®, a completely plant derived formulation.

39 year old male suffering from male pattern hair loss for 15 years gained a significant amount of hair with QR678®

PRE TREATMENT

POST 6 SESSIONS

25 year old female from alopecia areata, was also diagnosed with hypothyroid. She achieved impressive results with QR678, a completely steroid-off treatment.

PRE TREATMENT

POST 6 SESSIONS

39 year old male suffering from male pattern hair loss for 15 years gained a significant amount of hair with QR678

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HIGHLIGHTS IN MEDICAL CONFERENCES

CUTICON – December 2023

Dazzling moments at Cuticon 2023, Gujarat! QR678 Neo took centre stage, earning accolades from top medical professionals.
FADS – October 2023
QR678 Neo made it’s presence felt at FADS (Face Aesthetics Dermatologists Society), the 7th International Conference held at Goa. Renowned dermatologists got QR678 Neo administered and shared their positive experience.
CDCON – September 2022
QR678® Neo drew attention with an enlightening session and live demonstration at CDCON 2022 – a platform to challenge changing practices along the lines of Exploration and Innovation.

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FAQ'S

QR678® Neo is a mixture of natural growth factors that are already present in the scalp and therefore it is completely safe to use on everybody. It has the right concentration of specific hair growth factors and QR678® Neo does not have any side effects, is performed as an outpatient procedure and the results are visible within eight weeks of starting the treatment. You can listen for yourself what the patients say about QR678® Neo hair fall treatment https://www.youtube.com/watch?v=pIvjpQgSsrc

QR678® Neo injections are administered in 8-12 sessions in about 3-4 weeks apart. The results are visible after few weeks. Once you have achieved the desired results the injections need not be repeated unless the hair fall starts again. This is because QR678® Neo make the hair follicles healthy. Get to know more about why QR678® Neo is highly effective in treating hair fall and increasing hair growth. http://www.qr678.in/

QR678® Neo is a completely safe treatment without side effects and you can go about your daily routine after the sessions. The only care you need to take is to use a gentle shampoo not before the next day of the treatment and avoid scratching and rubbing the treating area. If you have any other problem then consult your dermatologist. https://www.youtube.com/watch?v=LNm2z3EGLxg

Yes, using QR678® Neo after hair transplant produces very successful results. QR678® Neo gives faster density and reduces the catagen loss of transplanted hair. The growth factors in QR678® Neo help in faster healing and activate the dormant follicles and thus - Increase the viability of hair follicles - Improve healing and repairing of tissue process - Strengthen the inactive hair follicles and stimulate hair growth - Improves the health of existing hair and they will become fuller and stronger QR678® Neo can be given in multiple treatment sessions after three to four weeks after successful hair transplant surgery. QR678® Neo can also be used before the hair transplant surgery to reduce the area of transplant and  improve the results.

QR678® Neo is a relatively new treatment for hair fall and hair regrowth but in the short time of its invention QR678® Neo has proven to be more effective than PRP and stem cell treatment for reducing hair fall. QR678® Neo produces longer lasting and better results and is completely safe and without any side effects. QR678® Neo can help treat and rogenetic alopecia, female pattern hair loss, and hair loss because of chemotherapy, seborrheic dermatitis, and alopecia areata. PRP and stem cell on the other hand do not have the specific concentration of required growth factors, they lack standardisation in terms of treatment protocols and preparation of the solution injected and lack good quality studies to prove their benefits. produce guaranteed results and can cause tightness and tenderness in scalp, scar tissue formation, calcification of the injected points, and formation of scar tissues. Both processes are still under investigation and their results are still awaiting confirmation. Dr Rinky Kapoor of The Esthetic Clinics explains the difference between QR678® Neo and stem cell here: https://www.youtube.com/watch?v=wgNihm8ciu4 and https://www.youtube.com/watch?v=ZUWXKzVh0PM

Yes genetic hair loss can be treated if the treatment is started in time. Heredity hair loss usually runs in the family and can affect both men and women. If you too have a close elder relative who lost his or hair in a patterned baldness then you should keep a close eye on your hair too. Hereditary hair loss usually happens in a pattern; M or W shaped in men and along the hair part in women. See the doctor immediately if you suffer from hair loss. There are many common and successful treatments available for genetic hair loss which include

 

- Topical and oral medications: These include Minoxidil topical lotion and Finasteride tablets.

- Hair transplantation using FUT and FUE methods.

- Nutritional supplements: Your physician might also suggest some hair supplements that can help arrest hair fall. Dietary supplements containing Vitamin A, C, and Biotin, zinc, and iron can also help control hair fall caused because of genetics.

Alopecia post chemotherapy is a very common consequence of cancer treatments and therapies and it is often the most psychologically and socially devastating side effect. Many patients shy away from the treatments because of fear of hair fall and hair loss. However, in most cases, such alopecia is reversible but the recovery takes several months and even up to a year. Some basic latest treatment methods will speed up the healing: - Scalp Cooling: This is a FDA approved method for patients suffering from breast cancer. Scalp cooling or hypothermia results in constriction of the blood vessels in the scalp, which in turn leads to reduced delivery of chemotherapy to the hair. Scalp cooling devices consist of cooling unit that circulate the coolant on the scalp. This is done about 30 minutes before the start of chemotherapy. Patients can feel some mild discomfort, nausea, and dry skin because of scalp cooling. - Topical Minoxidil: Minoxidil helps by increasing the blood flow to the hair follicle thereby preventing miniaturization of hair follicle. - QR678® Neo hair regrowth treatment: QR678® Neo is a FDA approved, completely safe hair regrowth treatment that has no side effects or causes any discomfort to the patient. Clinical trials have proved QR678 to be effective in treatment of chemotherapy induced alopecia in both men and women. The results of QR678® Neo last lifelong.

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